進行性壊疽性鼻炎の一例 附 本邦最近11年間の文献的統計的観察

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概要

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• A case of progressive gangrenous rhinitis was reported. The patient was a 54-year-old male who unfortunately expired of intestinal bleeding and of liver damage. Initial symptoms were remittent fever with 38-39ª, fowel smelling rhinorrhea and obstruction of the nasal cavity. Partial resection of the right maxilla was performed and Endoxan (3800mg), Ra radiation (3880mgh), steroid hormone and antibiotics were ad-ministered. Owing to such treatment, the patient came to a state of lull. Duration of disease was 2 months.Pathological finding: nasal tissue showed diffuse granulomatous degeneration with marked necrosis and proliferation of a typical reticulum cell, and also, soft palate, tongue, tonsils, liver and spleen revealed similary finding. Moreover, we total protein fraction, immuno-electrophoresis of serum and plasmin were ex-amined.In resent 11 years, 172 cases of progressive gangreneous rhinitis were reported in Japan. One hundred forty-four cases of these reported in literatures of this country. We reviewed & discussed those cases included 103 males and 41 females cases. The youngest patient was 11 years old, the oldest one was 77 years old. Most patients being affected by the disease were from 20 to 40 years old. Fourteen cases out of 144 (15%) were proven to have contributory factors. The majority of those were rhinological operation; polysinectomy, polypotomy and conchotomy, etc. Initial region of this disease was in the nasal cavity, external nose and palate, etc. The nasal cavity corresponded with 50% of all initial region. In 95 cases an initial region spread to the other regions; Increasing odor in the nasal cavity, palate, neck, pharynx and submandibular region.In 60 autopsies, 29 cases showed inflamatory finding and 31 cases showed tumorous finding, In the cases diagnosed as tumor microscopically, 11 cases of reticulosarcoma, 10 cases of sarcoma and 8 cases of granulomatosis were recongnized. Eighty-five patients died. Lethality rate was 80%. Duration of the disease in deceased cases was within a year.

• 社団法人 日本耳鼻咽喉科学会の論文

著者

• 中川 透

  慶応義塾大学医学部耳鼻咽喉科学教室

• 佐々木 順一

  慶応義塾大学医学部耳鼻咽喉科学教室

• 中川 透

  慶応義塾大学医学部耳鼻咽喉科教室

• 来間 数雄

  警友総合病院耳鼻咽候科

• 桜井 栄

  慶応義塾大学医学部耳鼻咽喉科教室

• 佐々木 順一

  慶応義塾大学医学部耳鼻咽喉科教室

• 来間 数雄

  警友総合病院耳鼻咽喉科

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• 進行性壊疽性鼻炎の一例 附 本邦最近11年間の文献的統計的観察

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