INVESOIGATION ON THE VESTIBULAR RECRUITMENT PHENOMENON SECOND REPORT EXPERIMENTAL OBSERVATION:SECOND REPORT EXPERIMENTAL OBSERVATION

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The author elucidated, as described in the first report the existance of the vestibular recruitment in Meniere's disease from a number of clinical observations. In the present experiment, in order to further clarify the relationship between the realization of the vestibular recruitment and the incidence of vestibular disturbances, histological changes in the vestibular labyrinth of the rabbit were studied by means of intratympanic injections of a local anesthetic (lidocaine) and some metabolic inhibitors (FNa, KCI, CaC12 and monoiod acetic acid) or by an ultrasonic beam directed to the vestibular labyrinth.The results obtained are summarized as follows :1. The vestibular recruitments were observed in many cases which showed reversible histological changes in the labyrinth, but not in cases with irreversible changes.2. The histological changes in cases with positive vestibular recruitment were well localized in the crista ampullaris in cupula but other parts were intact.3. The histological changes in cases with negative vestibular recruitment were intensively extended to all the labyrinthine structure.4. Therefore, from both clinical and experimental observations, the author presumed that the origin of the vestidular recruitment is the disturbance of the hair cells in the peripheral cupular organ.
一般社団法人日本耳鼻咽喉科学会の論文