人間鼓室小骨のカルシウム量に関する研究
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概要
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Calcium values in auditory ossicles of 45 malleus and 40 incus from normal persons and 11 malleus and 10 incus from persons suffering from otitis media were quantitatively determined by the titrimetric method with ethylendiamine tetraacetic acid using "Sunchromine Fast Blue MB" as an indicatro. The magnesium content in ossicle was previously measured colorimetrically with Titan Yellow reagent, and the bone magnesium turned out to be no obstacle to the calcicm determination.In normal ossicles, contents of calcium in malleus and incus were 27.30±1.64% (by weight) and 26.77±1.76% respectively, regardless of sex or age. The local calcium content of each ossicles was highelst in capitulum and corpus incudis, the next in collum mallei, and lowest in crus longus and manubrium mallei, as follows; capitulum 26, 70±2.50%, collum mallei 24.30±2.83%, manubrium mallei 13.50±3.58%, corpus incudis 26.90±3.12%, and crus longus 22.55±4.17%.In specimens with otitis media, the content of calcium of the auditory ossicle, especially that of the incus, was lower than that of normal ones. Thus, values of 25.81±2.02% for malleus and 23.37±2.17%for incus were obtained.