拘束性肺疾患症例における肺葉切除後の残存肺機能予測の検討

概要

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In a series of patients receiving lobectomies for lung cancer, we compared predictions of postoperative respiratory function values in those with restrictive lung disease (n=13) and those without (control group, n=41). Respiratory function was tested before and after surgery : FVC, FEV1.0, TLC, FRC, RV, DLco. The lung perfusion scanning test was also performed before operation. Postoperative values were predicted by Ali's formula. The correlation between the predicted and measured postoperative respiratory function values was very close in either group, but between two the groups there were no parallel rows for FVC, FEV1.0, TLC, FRC, RV or DLco in the analysis of covariance. Slopes of regression lines for FVC, FEV1.0, TLC in the restrictive group were steeper than those in the control group. For FRC, RV and DLco the slopes in the restrictive group were less steep than those in the control group. We conclude that it is difficult to predict postoperative respiratory function in patients with restrictive lung disease.
特定非営利活動法人日本呼吸器外科学会の論文