The Effect of Pulmonary Hypertension on the Elastic Structure of the Pulmonary Trunk

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概要

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• Microscopic studies of the pulmonary trunk in pulmonary hypertension of 28 cases and control groups of 65 cases ranging from the age of 1 to 83 years were carried out.The elastic configuration of the media of the pulmonary trunk was classified into 5 types and relationship between the severity of the pulmonary hypertension and changes of the elastic fibers in the media was carefully studied.As a result, increase of the elastic fibers even in the acquired severe pulmonary hypertension was observed.This finding is compatible to the views of Meyer although the methods of observation differ and is contradictory to the conclusions of Heath and Saldaiia.Marked changes of the elastic fibers in the media of pulmonary trunk was not found in dogs injected with lycopodeum spores, which may be due to the short duration of pressure loading.A close relationship of the elastic fibers with the smooth muscle cells was observed in the electron microscopic studies of animal experiments.

• International Heart Journal刊行会の論文

著者

• Yamakawa Kunio

  2n Div. Dept. Of Intern. Med. Juntendo Univ. School Of Med.

• Takagi Toshitaka

  Department Of Orthopaedic Surgery Yokohama City University School Of Medicine

• YAMAKAWA Kunio

  Second Department of Internal Medicine, Juntendo University, School of Medicine

• KITAMURA Kazuo

  Second Department of Internal Medicine, Juntendo University, School of Medicine

• SUGANO Tatsuko

  Second Department of Internal Medicine, Juntendo University, School of Medicine

• UESUGI Masahide

  Second Department of Internal Medicine, Juntendo University, School of Medicine

• TAKAGI Kohko

  Second Department of Internal Medicine, Juntendo University, School of Medicine

• YAMANAKA Yoshitada

  Second Department of Internal Medicine, Juntendo University, School of Medicine

• Yamakawa K.

  Second Department of Internal Medicine, Juntendo University, School of Medicine

• TAKAGI Toshitaka

  Department of Pathology, Juntendo University, School of Medicine

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