High Incidence of Subclinical Peripheral Neuropathy in Myelitis with HyperIgEaemia and Mite Antigen-specific IgE (Atopic Myelitis): An Electrophysiological Study.

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Objective To study subclinical involvement of the peripheral nerves in myelitis with hyperlgEaemia and mite antigen-specific IgE (atopic myelitis: AM). Material and Methods We carried out a nerve conduction study of the median, ulnar, tibial, and sural nerves in 21 patients with AM and in 28 patients with clinically definite or laboratory-supported definite multiple sclerosis (MS). Results The patients with AM showed a significantly higher frequency of abnormal records than the MS patients in the sensory nerve conduction study (52.4% vs. 14.3%, p=0.0106). The frequency of abnormal records in the motor nerve conduction study in AM patients was twice as high as in MS patients (38.1% vs. 17.9%), but the difference was not statistically significant. Abnormality in the F-wave-evoked frequency in the median nerve was also significantly more common in AM patients than in MS patients (57.9% vs. 10.7%, p=0.0016). Conclusions These findings suggest that subclinical peripheral neuropathy is frequent in patients with AM. (Internal Medicine 41: 684-691, 2002)
社団法人　日本内科学会の論文