Vascular Lesions in Experimental Renal Hypertension, with Special Reference to Effect of Hypotensive Treatment

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概要

• 論文の詳細を見る

• Experimental renal hypertension was produced in the rabbit by a modified Goldblatts technic. The small arteries and arterioles in the brain and heart were morphologically estimated and “ratio of wall to diameter” of various sizes of vessels was calculated and plotted on a semilogarithmic chart. Thus a mean curve pattern of ratios of wall to diameter along the course of arterioles (arteriolar profile chart) was obtained. These patterns of ratios of “arteriolar profiles” were correlated to the levels of blood pressure. Hypertensive arteriolar reaction was featured by an increase in the ratios of wall to diameter in vessels of some 100μ. in diameter. This was, however, reversed by effective hypotensive therapy.Cerebral hemorrhage was seen only in the hypertensive non-treated animals. Possible relationship between arteriolar thickening and cerebral hemorrhage was postulated.

• International Heart Journal刊行会の論文

著者

• Takeuchi Jugoro

  Second Department of Internal Medicine, Tokyo Medical And Dental University

• Takauchi Jugoro

  2nd Division Dept. Of Intern. Med. Tokyo Univ. Sch. Of Med. And 1st Division Dept Of Intern. Med. Ka

• TAKEDA Tadanao

  Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• SHINTANI Fujio

  Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• UCHIDA Eiichi

  Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• OKADA Ryozo

  Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• Takeuchi J.

  Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo

• TAKEDA Tadanao

  Second Department of Internal Medicine and the Department of Thoracic Surgery, Faculty of Medicine, University of Tokyo

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