Periodic fluctuation of blood pressure and its management in a patient with pheochromocytoma. Case report and review of the literature.:Case Report and Review of the Literature
スポンサーリンク
概要
- 論文の詳細を見る
The case of a 69 year old man with a right adrenal pheochromocytoma who manifested cyclic fluctuations of blood pressure with a cycle length of 9 to 13 min is reported. We collected and reviewed 14 similar cases previously reported in the literature. In these cases, right adrenal pheochromocytoma was most common, while 1 case involved the left adrenal and 2 cases were of extra-adrenal origin. The incidence in males was twice that in females and the median age was 45.3 years. Although a good correlation between the blood pressure and plasma norepinephrine concentrations was observed in our patient, the exact mechanism for the cyclic fluctuations of blood pressure is not known. In our patient, both YM-09538 and bunazosin were effective in controlling severe hypertension preoperatively. YM-09538 induced significant increases in urinary norepinephrine concentrations (1327±238μg/day), while bunazosin induced a significant decrement in urinary norepinephrine concentrations (475±188μg/day) compared with pretreatment levels (900±42μg/day) (p<0.01). These observations indicated that bunazosin as a postsynaptic α-adrenergic receptor blocker interfered with release of norepinephrine from the tumor and thus might be beneficial in the management of elevated blood pressure in patients with pheochromocytoma.
- International Heart Journal刊行会の論文
著者
-
UMEDA Teruhisa
Third Department of Internal Medicine Medical School, Kumamoto University.
-
SATO Tatsuo
Third Department of Internal Medicine Medical School, Kumamoto University.
-
UMEDA Teruhisa
Third Department of Internal Medicine, Faculty of Medicine, University of Kumamoto
-
OISHI Seiichi
Third Department of Internal Medicine, Faculty of Medicine, University of Kumamoto
-
SASAKI Masato
Third Department of Internal Medicine, Faculty of Medicine, University of Kumamoto
-
OHNO Miho
Third Department of Internal Medicine, Faculty of Medicine, University of Kumamoto
-
UMEDA Teruhisa
Third Department of Internal Medicine Kumamoto University Medical School
関連論文
- THE EFFECTS OF THE RESPIRATORY CYCLE BY MECHANICAL VENTILATION ON CARDIAC OUTPUT MEASURED USING THE THERMODILUTION METHOD
- High Plasma Renin Activities in Primary Aldosteronism with Malignant Hypertension : A Case Report
- Periodic fluctuation of blood pressure and its management in a patient with pheochromocytoma. Case report and review of the literature.:Case Report and Review of the Literature
- (Na++K+) ATPase inhibitors and intracellular electrolytes in essential hypertension.
- Pharmacokinetics of Intravenous Famotidine in Elderly Patients with and without Renal Insufficiency and in Healthy Young Volunteers.
- Cytomegalovirus Infection Associated with Acute Pancreatitis, Rhabdomyolysis and Renal Failure.
- Serum angiotensin converting enzyme (S-ACE) activity in patients with chronic renal failure on regular hemodialysis.