Effects of β-Blocker (Propranolol) on the Blood Pressure and Eye-Ground of Spontaneously Hypertensive Rat Fed with High-Salt Diet
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概要
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Beta-blocker (propranolol 10mg/Kg body weight, daily) in modest dose lowers the level of blood pressure, decreases the weight of the heart after 10 weeks' administration since 6 weeks age in male Spontaneously Hypertensive Rats. The lowered level of blood pressure in SHR with high-salt diet and β-blocker is similar to the level of SHR with common diet. The β-blocker dilates the sapstic artery in the eye-ground of SHR with high-salt diet and increase the ratio of the caliber of artery/vein.
- International Heart Journal刊行会の論文