Assessment of Left Ventricular Contraction and Relaxation by Systolic and Diastolic Time Intervals Measured from the First Derivative of Apexcardiogram in Cardiomyopathy

スポンサーリンク

概要

• 論文の詳細を見る

• To determine the usefulness of the time intervals obtained from the first derivative of apexcardiogram (dA/dt) in assessing contraction and relaxation in cardiomyopathy, 11 patients with hypertrophic obstructive cardiomyopathy (HOCM) and 9 patients with congestive cardiomyopathy (COCM) with hemodynamically and angiographically documented diagnosis were studied. As a control group 50 normal subjects were used. Since contraction and relaxation is dependent on preload and afterload, the time interval from R wave of electrocardiogram to the positive peak of dA/dt (R to dA/dt) and 2 relaxation parameters derived from negative peak dA/dt, early relaxation index (ERI) and total relaxation index (TRI) were investigated. In HOCM the R to dA/dt were shortened (55±13msec versus 76±14msec in controls, P<0.01) and both ERI and TRI were augmented (ERI: 12.5±9 versus 4.3±5 in controls, p<0.001; TRI: 147±29 versus 70±18 in controls, p<0.02). In COCM the R to dA/dt were elongated (124±14msec versus 76±14msec in controls, P<0.001) and both ERI and TRI were decreased (ERI: 2.1±4 versus 4.3±5 in controls, p<0.005; TRI: 41±17 versus 70±18 in controls, p<0.002). Significant correlation between these indices and some internal parameters of myocardial performance were observed.These findings indicate that systolic and diastolic time intervals measured from the first derivative of apexcardiogram may by used as a reliable indices for evaluation of contraction and relaxation independently of preload and afterload.

• International Heart Journal刊行会の論文

著者

• KOLEV Nikolai

  Medical Academy, Higher Medical Institute, Department of Internal Medicine

• CSERHALMI Livia

  Hungarian Institute of Cardiology, Semmelweis University, Department of Cardiology

• PALIK Imre

  Hungarian Institute of Cardiology, Semmelweis University, Department of Cardiology

• ROMODA Tibor

  Hungarian Institute of Cardiology, Semmelweis University, Department of Cardiology

• CSERHALMI Livia

  Hungarian Institute of Cardiology, Semmelveis University, Department of Cardiology

• ROMODA Tibor

  Hungarian Institute of Cardiology, Semmelveis University, Department of Cardiology

関連論文

• Assessment of Left Ventricular Contraction and Relaxation by Systolic and Diastolic Time Intervals Measured from the First Derivative of Apexcardiogram in Cardiomyopathy
• Influence of Acute Hemodynamic Changes on the Peak Velocity of Contractile Element Shortening and Maximum Velocity Obtained by the Calibrated Apex Cardiography in Dogs
• Combined echo-apexcardiographic assessment of left ventricular function in cardiomyopathy.

スポンサーリンク