Study of the Immuno-Genetical Correlation of the Pig Lymphocyte Antigens and the Major Histocompatibility Complex

概要

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In order to investigate the immuno-genetical correlation of the pig lymphocyte antigens and the major histocompatibility complex, the lymphocyte 18 of littered pigs and 51 non-littered pigs have been carried out the mixed lymphocyte culture (MLC) reaction. The results obtained were summarized: 1) the mean value of cpm count per minute by autologous cells of 18 littered pigs were 441±53 in the 1-way method 685±94 in the 2-way method. And mean value of cpm by allogeneic cells were 4174±260 in the 1-way method and 3648±403 in the 2-way method. 2) The mean value of cpm by autologous cells of 51 non-littered pigs were 522±36 in the 1-way method and 533±39 in the 2-way method. The mean of cpm by allogeneic were 7360±322 in the 1-way and 7400±561 in the 2-way method. 3) In 8 littered pigs, the identical sibling groups of SLA antigens were No. 3-No. 7 and No. 5-No. 8. The resembling groups of histocompatibility antigens were No. 1-No. 6-No. 8 and No. 2-No. 3-No. 4-No. 5-No. 7. Therefore, the histocompatibility antigens by MLC could not be always agreement with the SLA antigens.
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