牧草中のエストロジェン様物質の投与によるハムスターの正常雄と去勢雌の体成分の変化
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The data presented in the previous paper have demonstrated that the growth of intact male and spayed hamsters were accelerated by oral administration of estrogenic substances in herbage. The present paper reports the effects of oral administration of diethylstilbestrol (DES), genistin and alfalfa-extract on the organ weight and body composition of intact male and spayed hamsters.The results were summarized as follows:1) In the case of intact male hamsters, the growth of the body length and femur length were accelerated by DES, genistin and alfalfa-extract, and the liver weight and spleen weight were increased. DES had a depressing effect on the adrenal weight, and alfalfa-extract had an increasing effect on the weight of anterior lobe of pituitary. DES decreased the seminal vesicles weight and testes weight, whereas genistin and alfalfa-extract increased the weights of these organs.The gains of fat and water in the treated animals were larger than those of the control.The percentage of fat increased significantly, though the percentages of water and fat-freesolid in the treated animals were not different from those of the control. The increase of subcutaneous fat was particularly noteworthy.2) The fat deposition and the weight of anterior lobe of pituitary were increased and the liver weight and the adrenal weight were decreased by spaying, though the spayed hamsters did not gain the body weight faster than the intact female hamsters.3) In the case of spayed hamsters, DES, genistin and alfalfa-extract accelerated the growth of body length and femur length and increased the liver weight and kidney weight, however, these substances did not affect the adrenal weight and uterine weight. The percentage of fat in the treated animals increased and the increase of ubcutaneous fat was most noteworthy. The percentage of fat-free solid was decreased by DES administration, though genistin and alfalfa-extract gave no effect on the percentage of fat-free solid in the spayed hamsters.
- 公益社団法人 日本畜産学会の論文
公益社団法人 日本畜産学会 | 論文
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