雛に対するMoenomycinの生物学的作用
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概要
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Moenomycin (Flavophospholipol ®) is a new antibiotics which is active against grampositive organisms and is produced by Streptomyces bambergiensis, S. ghanaensis, S. ederensis, and S. geysiriensis. Experiments were conducted to determine the growth promotion and the other biological effects of moenomycin in chickens. Day old single comb White Leghorn cockerels obtained from a commercial hatchery were used. Moenomycin was fed to chickens at the dietary level of 10 ppm for 2 or 4 weeks. The results were as follows. Moenomycin caused a significant increase in body weight and improvement in feedefficiency than the controls. At the level of moenomycin there was no detectable effect on the pH and lactic acid content as well as the counts of enteric bacteria, staphylococci, streptococci and lactobacilli in the small intestine and caecum. Values of biochemical analysis of the serum of the moenomycin treated chickens with regard to alkaline phosphatase activity, total protein, total cholesterol, glucose and lactic acid were all within normal ranges. The higher alkaline phosphatase activity observed in the younger cockerels was seemed to be the reflection of age effects. Although moenomycin might be correlated with a decrease in weights of the small intestine and the caecum, the weights of the other organs did not decrease. These results as a whole suggest that growth stimulation of moenomycin may be the results of direct action of the antibiotics to the intestinal wall that would induce increased efficiency in absorption of nutrients,
- 公益社団法人 日本畜産学会の論文
公益社団法人 日本畜産学会 | 論文
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