大脳皮質SIニューロンのシナプス電位

概要

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In order to clarify the synaptic organization of somatosensory cortical neurons (SI neurons) in a cat, this experiment focused on the classification of SI neurons from the postsynaptic potentials evoked by skin volley of contralateral forlimb. Out of 100 explored neurons, many SI neurons showed the EPSP-IPSP sequency of potentials by skin volley. Especially, a long-lasting hyperpolarization evoked by skin afferents was remarkable on SI neurons. For example, SI neurons with 70mV spike height elicited the long duration of IPSP (200msec) with 15mV amplitude by skin volley. From the shift of equilibrium potential by Cl ion injection, ionic mechanism for IPSP on SI neuron was enhancement of Cl permeability on subsynaptic membrane. And it was speculated that the location of inhibitory synapse was on soma membrane, because the IPSP was sensitive to injected currents. Simultaneous recording on both VPL neuron extracellulary and SI neuron intracellulary was succeeded, and it was speculated that a VPL neuron and a SI neuron played on the acceptance of sensory information as a physiological unit. This experiments were done with Dr. S. Andersson and Dr. I. Lehtinen in sweden.
日本生物物理学会の論文