腎近位尿細管細胞膜におけるイオン透過性-1-K及びHCO3イオンの基底側膜電位形成に於る役割

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概要

• 論文の詳細を見る

• Using a semi-floating glass microelectrode, the permeability of the peritubular membrane for Na, K. HCO<SUB>3</SUB> and Cl was studied in the rat kidney proximal tubule in vivo. The magnitude of the change in membrane and transepithelial p.d. due to peritubular ionic replacement was analyzed by means of an equivalent circuit analysis. The results of the present study showed that the peritubular p.d. is composed mostly of the diffusion p.d. of K and HCO<SUB>3</SUB>. The contribution of Na and Cl to the membrane current appears to be negligible. The transference number of the peritubular cell membrane was 0.57 for K, 0.42 for HCO<SUB>3</SUB> and less than 0.01 for Na.

• 日本生物物理学会の論文

著者

• 佐藤 賢三

  マックスプランク生物物理研究所及びニューヨーク州立バッファロー大学

関連論文

• 腎近位尿細管細胞膜におけるイオン透過性-1-K及びHCO3イオンの基底側膜電位形成に於る役割

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