The new FioreDB database provides comprehensive information on plant transcription factors and phenotypes induced by CRES-T in ornamental and model plants

概要

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FioreDB (http://www.cres-t.org/fiore/public_db/) is a database of phenotypes induced by Chimeric REpressor gene-Silencing Technology (CRES-T) in ornamental and model plants. CRES-T induces a loss-of-function phenotype of a transcription factor (TF) gene by expression of a chimeric repressor produced by fusion of a TF to the strong transcriptional repression domain (SRDX). The earlier version of FioreDB provided phenotypic information induced by many kinds of chimeric repressors in various plants including torenia, chrysanthemum, cyclamen, gentian, morning glory, lisianthus and Arabidopsis. Phenotypic information, however, was not linked with gene information. We report here the development of the new FioreDB that provides more than 300 phenotypic information of various plants, linked to more than 100 TFs. FioreDB also provides information about classification of TFs, putative repression motifs found in TFs and other proteins, and incorporates publicly available gene information such as sequences and microarray data for all Arabidopsis genes. The new FioreDB described here, will be a valuable resource for basic research of TFs and for the manipulation of traits of agronomically important plants by CRES-T, especially from the point of view of horticulture.