Clinical Outcomes and the Risk Factors of Coronary Artery Aneurysms That Developed After Drug-Eluting Stent Implantation
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概要
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Background: There is only limited data on coronary artery aneurysms (CAA) after drug-eluting stent (DES) implantation. Methods and Results: Two hundred-fifty one patients who had 2 angiographic follow-ups at 8 months and 28-36 months, respectively, after the index procedure with DES from 2003 to 2007 were enrolled. A CAA was defined as a localized dilatation exceeding 1.5 times the diameter of the adjacent artery. The independent risk factors and major adverse cardiac events (MACE) were determined, including cardiac death, myocardial infarction (MI) and target-vessel revascularization (TVR), between the patients with CAA (n=35) and without them (n=216). On multivariate analysis, a lesion in an infarct-related artery (IRA) (odds ratio (OR): 6.1, P=0.001), a lesion in the left anterior descending artery (OR: 4.9, P=0.005), a lesion length >33mm (OR: 3.9, P=0.022), and a lesion with chronic total occlusion (CTO) (OR: 3.4, P=0.044) were the independent risk factors for CAA. Follow-up duration was 1,046±516 days. Although most patients (71.4%) were asymptomatic, MACE was found in 10 patients (28.6%). No deaths occurred. MI with stent thrombosis occurred in 5 patients (14.3%) and TVR occurred in 10 patients (28.6%). Conclusions: The risk factors for the development of CAA after DES are a long lesion over 33mm, a lesion in the left anterior descending artery, a lesion in an IRA, and CTO. Long-term follow-up and large clinical trials are warranted for patients with CAA. (Circ J 2011; 75: 861-867)
論文 | ランダム
- 絵画と思想(第2回)ハンス・ホルバイン--死に至る遠近法
- 単層構造マルチタッチ容量方式タッチパネルの開発(発光型/非発光型ディスプレイ,テーマ:ディスプレイに関する技術全般:LCD(バックライトを含む),PDP,有機/無機EL,CRT,FED,VFD,LEDなどのディスプレイに関するデバイス,部品,材料及び応用技術)
- タッチパネルを用いた没入型AR空間内の仮想物体の遠距離操作方法(MR/ARの実用化に向けたCV/PR技術の課題と展望)
- タッチパネルを用いた没入型AR空間内の仮想物体の遠距離操作方法(MR/ARの実用化に向けたCV/PR技術の課題と展望)
- タッチパネルを用いた難聴児・者への言語学習支援