Serotypes, Antimicrobial Susceptibility, and Minimal Inhibitory Concentrations of Actinobacillus pleuropneumoniae Isolated from Slaughter Pigs in Taiwan (2002–2007)
スポンサーリンク
概要
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In total, 211 isolates of A. pleuropneumoniae were collected from pigs with hemorrhagic pneumonia at slaughterhouses during 2002–2007. Serotypes, antimicrobial susceptibility and minimum inhibitory concentration (MIC) values were determined for each isolate of A. pleuropneumoniae to 10 antimicrobial agents. Serovar 1 of A. pleuropneumoniae was predominant in Taiwan in 138 of the 211 isolates, followed by serovars 2 and 5. More than 90% of collected isolates were sensitive to ceftiofur, cephalothin, and chloramphenical. However, lincospectin and gentamicin were relatively less susceptible with sensitivities of only 2.4 and 5.7%, respectively. Additionally, ceftiofur had the highest in vitro activity with an MIC50 of 2.2 μg/ml, followed by cephalothin (2.7 μg/ml) and chloramphenicol (7.9 μg/ml). Lincospectin had the least activity with MIC50 and MIC90 values of 73.9 and 114.5 μg/ml, respectively. The data indicate that ceftiofur and cephalothin were extremely active against A. pleuropneumoniae and with minimum MIC values. These drugs are suitable for controlling and treating hemorrhagic pleuropneumonia outbreaks in swine.
著者
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YANG Cheng-Yao
Division of Animal Medicine, Animal Technology Institute Taiwan
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CHANG Tsung-Chou
Department of Veterinary Medicine, National Pingtung University of Science and Technology
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CHIOU Ming-Tang
Department of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology
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LIN Chuen-Fu
Department of Medical Laboratory Science and Biotechnology, Central Taiwan University of Science and Technology
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CHANG Tsung-Chou
Department of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology
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LIN Chao-nan
Department of Mechanical and Automation Engineering Da-Yeh University
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