声門上部に発生した喉頭 MALT リンパ腫の 2 例

概要

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MALT lymphoma is a malignant lymphoma arising from mucosa-associated lymphoid tissue (MALT). Two cases of supraglottic MALT lymphoma of the larynx are presented. Case 1 was a 33-year-old female. During the initial consultation, the patient complained of pharyngodynia and hoarseness that had persisted for a month. Endoscopic examination revealed a supraglottic mass with a smooth surface. The histopathological diagnosis was MALT lymphoma. No other lesions were detected in a systemic evaluation. The patient was diagnosed as having clinical stage IE and was treated with 3 courses of R-CHOP followed by 30.6 Gy of radiotherapy. Case 2 was a 35-year-old female complaining of hoarseness. Multiple smooth lesions were exhibited in the supraglottic region. The diagnosis was MALT lymphoma in clinical stage IE. The patient was treated with the same protocol as Case 1. Both patients are alive with no evidence of recurrence at present.