肝細胞癌10年以上長期生存におけるMCNの役割

概要

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Between July 1994 and December 2008, 776 patients received their initial therapy for HCC in our institute. Of these, 18 patients have lived for more than a decade. Microwave coagulo-necrotic therapy (MCN) was performed in 14 patients and hepatic resection (HR) in 4.These patients were significantly younger (58.5 vs 66.9years old, p = 0.0002) and had a better liver function than the patients who have lived for less than 10 years (especially, serum albumin ; 4.09 vs 3.75, p = 0.0046).Of 18 patients, 14 patients had recurrences after on average 2,139 post operative days. For these recurrences, MCN was done as much as possible, because according to our last experience, we think that MCN has good efficacy for loco-regional control of HCC, comparable with that of Hr and MCN is especially good at multiple state of HCC and good for the patients with poor liver function. Average times of loco-regional therapy for recurrence were 3.00.Important feature for the long-term survival of patients with HCC include: preservation of hepatic function and repeating the radical therapy, MCN for initial or recurrent HCC.