Image-based Diagnosis of Alzheimer-type Dementia : Measurements of Hippocampal and Ventricular Areas in MR Images
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概要
- 論文の詳細を見る
We studied the possibility of objective diagnosis of Alzheimer-type dementia through radiological findings by evaluating cerebral and hippocampal atrophy in magnetic resonance images of patients with dementia. A statistically significant difference was seen in the hippocampus area index (HAI) and the ventricle area index (VAI) of healthy elderly individuals. Discriminant analysis with these two indexes demonstrated a sensitivity of 90.2% and a specificity of 81.8%, with an overall accuracy of 87.7%. Multiple discriminant analysis with VAI and HAI by stage of dementia showed an overall accuracy of 61.6% for discrimination of four stages. These results indicate that quantitative magnetic resonance imaging measurements can be used as an objective diagnostic technique for Alzheimer-type dementia.
- 日本磁気共鳴医学会の論文
- 2002-04-01
著者
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Fukumoto Ichiro
Institute Of Biomedical-engineering Graduate School Of Engineering Nagaoka University Of Technology
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Fukumoto Ichiroh
The Iastitute Of Biomedical Engineering Nagaoka University Of Technology
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Kodama Naoki
The Iastitute Of Biomedical Engineering Nagaoka University Of Technology
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Shimada Takamasa
Department Of Information Environment Integration And Design Tokyo Denki University
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KODAMA Naoki
Institute of Biomedical Engineering, Nagaoka University of Technology
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SHIMADA Tetsuo
Institute of Biomedical Engineering, Nagaoka University of Technology
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Fukumoto Ichiro
The Iastitute Of Biomedical Engineering Nagaoka University Of Technology
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