Outcome of One-year of Specialist Care of Patients with Type 2 Diabetes: A Multi-Center Prospective Survey (JDDM 2)

スポンサーリンク

概要

• 論文の詳細を見る

• OBJECTIVE: Specialist care is reportedly associated with favorable therapeutic results, although detailed outcomes of recent large-scale prospective surveys of specialist care have yet to be published. The goal of this study was to elucidate the effects of one years specialist care on the management of type 2 diabetes. PATIENTS AND METHODS: A multi-centered, prospective observational study was undertaken. 754 type 2 diabetes patients, who made their first visit to one of eleven participating outpatient clinics specializing in diabetes care, were enrolled. Routine structured diabetes care according to established guideline, including diabetes self-management education, was provided to all patients at each clinic visit. Parameters relating to glycemic control, serum lipids, blood pressure, patient follow-up status and others were followed for twelve months. RESULTS: The HbA1C level had improved significantly from 8.4±2.2% at baseline to 6.8±1.2% after six months and was 7.0±1.3% after twelve months (mean±SD). The higher the baseline HbA1C level, the greater the subsequent improvement. Moreover, the most dramatic improvements in HbA1C levels were seen within the first three months. The proportion of patients satisfying all of the therapeutic goals was extremely low at baseline and remained at less than 10% after twelve months of specialist care. CONCLUSIONS: Diabetic patients under specialist care experienced substantial improvement, especially in glycemic control, as early as a few months after the first visit. However, 35 percent of patients dropped out during the 12-month study period and this is one area that needs to be improved.

著者

• TAKAGI Hirofumi

  School of Nursing, Faculty of Medicine, Toho University

• Sone Hirohito

  Department Of Endocrinology & Metabolism Department Of Sports Medicine University Of Tsukuba

• Yamada Nobuhiro

  Department Of Chemistry And Chemical Engineering Yamagata University

• KAWAI Koichi

  Kawai Clinic

• Kobayashi Masashi

  First Department Of Internal Medicine School Of Medicine Toyama Medical And Pharmaceutical Universit

• Kawai Koichi

  Kawai Clinic, Tsukuba

• Takagi Hirofumi

  School of Nursing and Health Care, University of Niigata

関連論文

• Polymorphisms of Apolipoprotein E and Methylenetetrahydrofolate Reductase in the Japanese Population
• 日本から発信する血管病のEBM(第16回)JDDM研究--JDDM研究会の一連の疫学調査結果
• MPO-ANCA関連腎炎を合併した2型糖尿病の1例
• Computerized diabetes care(CoDiC)の概要と活用 (新時代の糖尿病学(4)病因・診断・治療研究の進歩) -- (糖尿病のフォローアップシステム IT活用によるケアー体制の充実)
• 2型糖尿病患者に対する薬物療法開始薬剤としてのグリメピリド0.5mg投与の有用性
• 糖尿病合併症診断のポイント (新しい糖尿病の臨床) -- (糖尿病の診断)
• Basal-Bolus 療法を実施中の糖尿病患者を対象としたインスリン デテミルの夜間QOLおよび治療満足度に関する検討 : NPHインスリンを対照とした無作為化比較試験
• SPARC is a Major Secretory Gene Expressed and Involved in the Development of Proliferative Diabetic Retinopathy
• Identification of ISG12b as a Putative Interferon-inducible Adipocytokine which is Highly Expressed in White Adipose Tissue
• Distinct Effects of Pravastatin, Atorvastatin, and Simvastatin on Insulin Secretion from a β-cell Line, MIN6 Cells
• Effects of Atorvastatin on Glucose Metabolism and Insulin Resistance in KK/Ay Mice
• Cerebral Hemorrhagic Infarction after Radiation for Pituitary Adenoma
• Receptor-Type Protein Tyrosine Phosphatase ε (PTPεM) is a Negative Regulator of Insulin Signaling in Primary Hepatocytes and Liver
• 経口糖尿病薬治療において血糖コントロールが不十分な2型糖尿病患者を対象としたインスリン デテミルの第3相臨床試験 : NPHインスリンを対照薬とした, 経口糖尿病薬併用時の1日1回投与における有効性と安全性の検討
• Basal-bolus 療法を実施中のインスリン依存状態の糖尿病患者を対象としたインスリン デテミルの第3相臨床試験 : NPHインスリンを対照とした有効性および安全性の検討
• Klebsiella pneumoniae による肝膿瘍と転移性筋膿瘍を発症した2型糖尿病の1例
• 糖尿病学の今後の課題 (新時代の糖尿病学(1)病因・診断・治療研究の進歩) -- (序論)
• MS3-2 富山市神保地区における全住民を対象とした気管支喘息有症率およびQOLに関する全年齢階層別調査(アレルギー疾患の疫学調査とその方向性, 第19回日本アレルギー学会春季臨床大会)
• A Kindred of Familial Acromegaly without Evidence for Linkage to MEN-1 Locus
• Polymorphisms in Four Genes Related to Triglyceride and HDL-cholesterol Levels in the General Japanese Population in 2000
• Serum Lipid Survey and Its Recent Trend in the General Japanese Population in 2000
• 当科で経過観察中の生体膵腎同時移植を受けた1型糖尿病の2例
• Effects of Pioglitazone Hydrochloride on Japanese Patients with Type 2 Diabetes Mellitus
• 2型糖尿病患者における薬物療法に関する実態調査 (IV) : インスリン療法 : 投与方法と超速効型インスリンアナログ製剤の治療効果- (JDDM17)
• 2型糖尿病患者における薬物療法に関する実態調査(III) : インスリン療法患者の臨床像と血糖コントロールとの関連-(JDDM12)
• 2型糖尿病患者における薬物療法に関する実態調査(II) : 薬物療法と血糖コントロール-(JDDM7)
• JDCP研究 (糖尿病性細小血管症(第2版)--発症・進展制御の最前線) -- (大規模試験から得られた発症・進展制御のエビデンス)
• OE-044 Baseline Data of JPPP : The Large Randomized Controlled Trial of Primary Prevention by Enteric Coated Low-dose Aspirin in Japan.(Atherosclerosis, clinical(01)(IHD),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circul
• FRS-102 Event rates of Japanese patients with atherothrombosis : Results from the REduction of Atherothrombosis for Continued Health (REACH) Registry(Clinical Frontiers in Atherosclerosis(IHD),Featured Research Session,The 72nd Annual Scientific Meeting o
• Prevalence, Awareness and Treatment of Cardiovascular Risk Factors in Patients at High Risk of Atherothrombosis in Japan : Results From Domestic Baseline Data of the REduction of Atherotherombosis for Continued Health(REACH) Registry
• PJ-637 JPPP (Japanese Primary Prevention Project with Aspirin) : The Large-scale Randomized Controlled Trial of Primary Prevention by Enteric-coated Low-dose Aspirin(Atherosclerosis, clinical-13 (H) PJ107,Poster Session (Japanese),The 70th Anniversary Ann
• 5 International and National Cohort Study for the Clarification of the Characteristic of the Japanese Patients of Atherothrombosis(Comparison between Domestic and Overseas Clinical Evidence in Cardiology,Symposium 9 (SY9) (H),The 70th Anniversary Annual S
• Characterization of Japanese Patients with Atherothrombosis by Participating in the International Registry of REACH (REduction of Atherothrombosis for Continued Health)(How to Make Japanese Original Evidence in Cardiology, The 69th Annual Scientific Meeti
• Association between daily physical activity and neighborhood environments
• Components of Metabolic Syndrome and their Combinations as Predictors of Cardiovascular Disease in Japanese Patients with Type 2 Diabetes. Implications for Improved Definition. Analysis from Japan Diabetes Complications Study (JDCS)
• Cardiovascular Events in Patients with Type 2 Diabetes and Effects of Lifestyle Modifications : The Japan Diabetes Complications Study (JDCS)
• 1 Coronary Heart Disease and Metabolic Syndrome in Japanese Patients with Diabetes(Treatment Strategy Update for Coronary Artery Disease with Diabetes Mellitus,Topic 8 (TP8) (IHD),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation
• Eicosapentaenoic Acid Suppresses Basal and Insulin-Stimulated Endothelin-1 Production in Human Endothelial Cells
• A Japanese Patient with Lipoprotein Lipase Deficiency Homozygous for the Gly188Glu Mutation Prevalent Worldwide
• Questionnaire-based analysis of the current level of asthma control and management in Niigata Prefecture, Japan : Changes from 1998 to 2000
• Stress Relaxation of Polymer Solutions under Large Strain
• R46Q Mutation in the Succinate Dehydrogenase B Gene (SDHB) in a Japanese Family with both Abdominal and Thoracic Paraganglioma Following Metastasis
• Importance of Lipid Levels in Elderly Diabetic Individuals : Baseline Characteristics and 1-Year Survey of Cardiovascular Events
• 1 Elovl-6, a New Target for Treatment of Obesity-induced Insulin Resistance(Advanced Strategies in Cardiovascular Medicine and Translational Research,Presidential Planning Program,Special Program,The 72nd Annual Scientific Meeting of the Japanese Circulat
• Association between Body Mass Index and Core Components of Metabolic Syndrome in 1486 Patients with Type 1 Diabetes Mellitus in Japan (JDDM 13)
• Mizoribine, an inhibitor of inosine monophosphate dehydrogenase, inhibits interleukin-6 production by freshly prepared rheumatoid synovial cells
• 2型糖尿病患者における薬物療法に関する実態調査 (V) : -経口血糖降下薬とインスリンの併用療法 : 投与薬剤と臨床像の特徴-(JDDM19)
• A Hierarchical Regression Model for Dietary Data Adjusting for Covariates Measurement Error by Regression Calibration : An Application to a Large Prospective Study for Diabetic Complications
• Association between single nucleotide polymorphisms within genes encoding sirtuin families and diabetic nephropathy in Japanese subjects with type 2 diabetes
• Distribution of Solid Particles Lighter than Liquid in an Agitated Vessel Stirred by Dual Impellers
• The Effect of Docosahexaenoic Acid on Plasma Catecholamine Concentrations and Glucose Tolerance during Long-Lasting Psychological Stress : A Double-Blind Placebo-Controlled Study
• Multifaceted intervention to promote the regular visiting of patients with diabetes to primary care physicians : rationale, design and conduct of a cluster-randomized controlled trial. The Japan Diabetes Outcome Intervention Trial-2 study protocol
• Cryptococcal Pleural Effusion in a Patient with Chronic Renal Failure Receiving Long-term Corticosteroid Therapy for Rheumatoid Arthritis
• Outcome of One-year of Specialist Care of Patients with Type 2 Diabetes: A Multi-Center Prospective Survey (JDDM 2)
• DOIT-2 (糖尿病) -- (臨床分野での進歩)
• 糖尿病患者の喫煙状況と禁煙指導の必要性に関する研究(JDDM21)
• Even Low-Intensity and Low-Volume Exercise Training May Improve Insulin Resistance in the Elderly
• The initiation of insulin therapy in type 2 diabetic patients treated with oral anti-diabetic drugs : an observational study in multiple institutes across Japan(JDDM27)
• The Influences of Casein Phosphopeptides on Metabolism of Ectopic Bone Induced by Docosahexaenoic Acids on Acute Inflammation and Fatty Acid Composition in Rats.
• Development of Coronary Heart Disease and Cerebral Stroke in Japanese Elderly Patients with Nonalcoholic Fatty Liver Diseases
• Manifestations of Fulminant CD8 T-cell Post-transplant Lymphoproliferative Disorder Following the Administration of Rituximab for Lymphadenopathy with a High Level of Epstein-Barr Virus (EBV) Replication after Allogeneic Hematopoietic Stem Cell Transplant

もっと見る 閉じる

スポンサーリンク