A Longitudinal Study on the Nutritional State of Elderly Women at a Nursing Home in Japan
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概要
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Objective. Elderly people at nursing homes often suffer from malnutrition, which is characterized by a loss of muscle mass and hypoalbuminemia. This malnourished state is closely associated with an impaired activity of daily living (ADL). We analyzed the nutritional state of such elderly individuals longitudinally over 3 years by anthropometry, serum albumin, and muscle and fat volume as estimated by MRI. Patients and Methods. The subjects consisted of 16 elderly women aged 83 ± 7 (mean ± SD) years who resided at a nursing home in an urban area of central Japan. We determined their ADL levels using the Barthel Index (BI) at entry. Seven women belonged to group A (BI; 65-100), thus implying either a mild or no decline in ADL, while the other 9 were in group B (BI; 0-60) and they demonstrated a severe decline in ADL. We measured the following parameters every year from 2000 to 2003; anthropometry including height, body weight, arm circumference (AC), and arm muscle circumference (AMC), thigh muscle and fat volume as estimated by MRI [thigh muscle volume (TMV) and thigh fat volume (TFV)], serum albumin, and plasma amino acid levels by blood biochemistry. The anthropometric values were converted into percentages of the age-and sex-matched reference values for Japanese. Results. In all subjects, the TMV, %AMC, and serum albumin level decreased significantly during the three-year period (p<0.05, respectively). The change in TMV correlated significantly with those in the %AC and %AMC (p<0.05, respectively). Group B showed significantly larger decreases in the %AMC and serum albumin level than group A. Conclusion. Both the muscular and visceral protein levels were found to decrease with aging in the subjects at the nursing home. This decrease depends partly on the ADL level of each subject.
著者
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Mawatari Kazunori
Amino Acid Department, Ajinomoto Co., Inc.
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Kato Masahiko
School Of Life Studies Sugiyama Jogakuen University
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Nakamura Hironori
Department Of Applied Physics University Of Fukui
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Gomi Ikuko
Department Of Internal Medicine Gifu University Graduate School Of Medicine
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Fukushima Hideki
Department Of Internal Medicine Gifu University School Of Medicine
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Moriwaki Hisataka
Department Of Gastroenterology And Hematology Division Of Organ Pathobiology Gifu University School
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Shiraki Makoto
Department Of Internal Medicine Gifu University Graduate School Of Medicine
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Miwa Yoshiyuki
Department of Gastroenterology, Gifu University Graduate School of Medicine
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Miwa Yoshiyuki
Department of Internal Medicine, Gifu University School of Medicine
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Gomi Ikuko
Department of Internal Medicine, Gifu University School of Medicine
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Mawatari Kazunori
Amino Acids Department, Ajinomoto Co., Inc.
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Saito Masaya
Seki Chuo Hospital
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Kobayashi Hisamine
Applied Research Department, AminoScience Laboratories, Ajinomoto Co., Inc.
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