Buerger's disease manifesting nodular erythema with livedo reticularis
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概要
- 論文の詳細を見る
We report a patient with Buergers disease (BD) who showed painful nodular erythema with livedo reticularis as an initial symptom. The patient developed this cutaneous manifestation in both lower extremities, and a skin biopsy demonstrated perivascular infiltration of mononuclear cells in the border zone between the dermis and subcutaneous tissue. Both nodular erythema and livedo reticularis were successfully treated with oral prednisolone, but both feet developed necrosis with ulcerations and had to be amputated 1.5 years later because of acute gangrene. Histopathology of the amputated tissue showed acute inflammation and multiple thrombi with recanalization in the posterior tibial arteries, leading to a diagnosis of BD. This disease should be considered as a possible diagnosis in refractory patients with nodular erythema and livedo reticularis, particularly when ulcerations and necrosis rapidly worsen.
- JAPAN SOC INTERNAL MEDICINEの論文
著者
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Matsuda Masayuki
Department of Internal Medicine (Neurology and Rheumatology), Shinshu University School of Medicine
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Matsuda M
Department Of Biology School Of Medicine Kyorin University
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Nose Masato
Department Of Internal Medicine Division Of Nephrology And Rheumatology Aichi Medical University Sch
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Ikeda S
Department Of Applied Chemistry Faculty Of Science And Engineering Saga University
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Okuda Y
Department Of Applied Physics Tokyo Institute Of Technology
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Takanashi T
Department Of Forest Entomology Forestry And Forest Products Research Institute
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Ikeda Shu-ichi
Department Of Internal Medicine (neurology And Rheumatology) Shinshu University School Of Medicine
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Okuda Yasuaki
Department Of Internal Medicine Center For Rheumatic Diseases Dohgo Spa Hospital
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Takanashi Tetsuo
Department of Internal Medicine, Center for Rheumatic Diseases, Dohgo Spa Hospital
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Horigome Reiko
Department of Dermatology, Iida Municipal Hospital
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Nose M
Department of Pathology, Ehime University School of Medicine
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Horigome R
Department of Dermatology, Iida Municipal Hospital
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