Predictive Risk Factors for Pulmonary Oxygen Transfer in Patients Undergoing Coronary Artery Bypass Grafting.
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概要
- 論文の詳細を見る
The ratio of arterial oxygen tension to inspired oxygen fraction (PaO2 / FiO2) is a useful indicator for weaning patients from mechanical ventilation and a reliable predictor of pulmonary dysfunction after cardiac surgery. The aim of this study was to elucidate the patient characteristics and variables that affect the PaO2 / FiO2 ratio. Between 1994-1998, 167 patients who underwent coronary artery bypass grafting (CABG) were examined retrospectively. Spearman's correlation coefficients were calculated between the PaO2 / FiO2 ratio and intubation period, and length of ICU stay. Patients were then divided into two groups with a PaO2 / FiO2 ratio < 350 and PaO2 / FiO2 ratio 350. Univariate analysis of the putative risk factors was performed. A logistic regression model was developed to evaluate factors that would influence the PaO2 / FiO2 ratio. A significant correlation was observed between the PaO2 / FiO2 ratio and intubation period, and length of ICU stay. Univariate predictors of a PaO2 / FiO2 ratio < 350 were low body weight, low preoperative PaO2, long operation time, high FiO2, low postoperative PaO2, history of smoking, hypertension and opening of pleura (p < 0.05). Excellent prediction was found with a model consisting of preoperative PaO2 and hypertension. Conclusion: The results of this study suggest that patients with a low preoperative PaO2 or hypertension may need more careful peri- and postoperative management since these factors are closely associated with the PaO2 / FiO2 ratio.
- International Heart Journal刊行会の論文
著者
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Takamoto Shinichi
The Department Of Cardiothoracic Surgery Faculty Of Medicine University Of Tokyo
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Ohtsuka Toshiya
The Departments Of Cardiothoracic Surgery University Of Tokyo
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Kotsuka Yutaka
The Department Of Cardiothoracic Surgery Faculty Of Medicine University Of Tokyo
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Ohtsuka Toshiya
the Departments of Cardiothoracic Surgery, and Public Health, University of Tokyo
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Sato Hajime
Occupational Medicine, University of Tokyo
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Suematsu Yoshihiro
the Departments of Cardiothoracic Surgery, and Public Health, University of Tokyo
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Araki Shunichi
Occupational Medicine, University of Tokyo
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- Predictive Risk Factors for Pulmonary Oxygen Transfer in Patients Undergoing Coronary Artery Bypass Grafting.