Serum Nutritional Status of Tocopherol and Retinol Normalized to Lipids of Persons Living in the Southern Rural Terai Region in Nepal

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概要

• 論文の詳細を見る

• Objective: The present study examined the levels of serum α-Tocopherol (Toc), retinol (Ret), cholesterol (Chol) and triglycerides (TG), and their correlations in the sera of people in Nepal. Methods: The survey was conducted on the general populace in the agricultural Terai region in southern Nepal. The study population consisted of 93 males and 83 females aged 10–68 years. Serum Toc and Ret were measured by high-performance liquid chromatography. Results: No significant differences were observed between the genders for the average of total Chol (T-Chol) (140 and 145 mg/100 ml, respectively), HDL-C (45 and 47 mg/100 ml), LDL-C (94 and 97 mg/100 ml), and TG (106 and 110 mg/100 ml), and the ratio of LDL/HDL (2.16). The levels of mean Toc (4.32 and 4.27 μg/ml) were about the same for both genders, while the mean Ret levels were significantly higher for males (624 ng/ml) than for females (535 ng/ml) (p<0.001). A direct relationship was found between the levels of Toc and Ret (r=0.46, p<0.001 and r=0.28, p<0.05 for males and females, respectively). Serum levels of Toc and Ret were positively related to the levels of Chol (r=0.48 and r=0.58, p<0.001 for males and r=0.49, p<0.001 and r=0.33, p<0.01 for females, respectively) and TG (r=0.23 and r=0.28, p<0.05 for males and r=0.29, p<0.01 and r=0.28, p<0.05 for females, respectively). The ratio of Toc/TG normalized to serum TG was directly correlated to the ratio of Ret/TG (r=0.79 for males, and r=0.72 for females, p<0.001, respectively) and the ratios of Toc/TG and Ret/TG were negatively related to the LDL/HDL levels (r=−0.49 and r=−0.43, for males, and r=−0.46 and r=−0.57 for females, p<0.001, respectively). Conclusion: The levels of Toc and Ret were low in the sera of people living in the southern rural Terai region in Nepal, and it was found that lower levels of Toc and Ret normalized to TG increased the ratio of LDL/HDL. These results suggest that greater intake of foods rich in Toc and Ret should be encouraged to reduce the risk of coronary heart disease.

• 日本衛生学会の論文
• 2004-01-01

著者

• AOKI Yoko

  Department of Medical Genetics, Tohoku University School of Medicine

• Hayashi Eriko

  Department Of Health And Nutrition Graduate School Of Human Life Science Osaka City University

• Akai Yuko

  Department Of Health And Nutrition Graduate School Of Human Life Science Osaka City University

• Ohno Y

  Mukogawa Women's Univ. Hyogo

• Ohno Yoshimi

  Department Of Food Science And Nutrition School Of Human Environmental Sciences Mukogawa Women'

• Ohno Yoshimi

  Department Of Food Science And Nutrition School Of Human Environmental Science Mukogawa Women's

• NAGATA KUMIKO

  Department of Bacteriology, Hyogo College of Medicine

• RAI Shiva

  Department of EE, University of South Carolina

• Rai Shiva

  Department Of Ee University Of South Carolina

• Rai Shiva

  Department Of Microbiology Nepal Medical College

• TAMURA Toshihide

  Department of Microbiology, Hyogo College of Medicine

• HIRAI Kazuko

  Department of Health and Nutrition, Graduate School of Human Life Science, Osaka City University

• SHRESTHA Mathura

  Department of Community Medicine and Family Health, Institute of Medicine, Tribhuvan University, Kat

• Hirai K

  Department Of Health And Nutrition Graduate School Of Human Life Science Osaka City University

• Hirai Kazuko

  Department Of Health And Nutrition Graduate School Of Human Life Science Osaka City University

• Hirai Kazuko

  Department Of Health And Nutrition Faculty Of Human Life Science Osaka City University

• JINDAI Mayumi

  Department of Health and Nutrition, Graduate School of Human Life Science, Osaka City University

• HIGUCHI Hisa

  Osaka Joshigakuen Junior College

• MIZUNO Seiko

  Soai College

• Shrestha Mathura

  Department Of Community Medicine And Family Health Institute Of Medicine Tribhuvan University Kathma

• Hirai Kazuko

  Department Of Nutritional Biochemistry Faculty Of Science Of Living Osaka City University

• Ohno Yoshimi

  Department Of Physiology Ii Nara Medical University

• Nagata Kumiko

  Department Of Bacteriology Hyogo College Of Medicine

• SHRESTHA Mathura

  トリブバン大学医学研究所

• Jindai Mayumi

  Department Of Health And Nutrition Graduate School Of Human Life Science Osaka City University

• Tamura Toshihide

  Department Of Bacteriology Hyogo College Of Medicine

• Nagata Kumiko

  Department of Bacteriology and Hyogo College of Medicine

• Tamura Toshihide

  Department of Bacteriology and Hyogo College of Medicine

• AOKI Yoko

  Department of Food and Nutrition, Japan Women's University

• Nagata Kumiko

  Department of Bacteriology

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