Intravascular Ultrasound Correlates of Corrected TIMI Frame Count.
スポンサーリンク
概要
- 論文の詳細を見る
The TIMI frame count (TFC) is an index of coronary blood flow, and a correction in TFC (CTFC) for left anterior descending artery (LAD) has also been proposed. However, the relationship between TFC and intravascular ultrasound (IVUS) parameters of culprit coronary arteries has not been reported. The aim of this study was to investigate IVUS-derived correlates of TFC before and after stenting, and to assess the validation of its correction for LAD. The study population was comprised of 38 patients with acute coronary syndrome or stable coronary artery disease studied by IVUS before and after stenting (LAD 21, circumflex 8, right coronary artery 9). For LAD, CTFC was calculated by dividing the TFC by 1.7. Preintervention luminal % area stenosis was 82 ±12.3%. Pre-and postintervention target lesion lumen areas were 1.8 ± 0.5 mm2 and 8.5 ± 0.5 mm2 (P < 0.0001), and CTFC were 35.3 ±16.8 and 16.9 ± 4.3 (P < 0.0001), respectively. In the 76 IVUS studies, CTFC showed a good correlation to luminal % area stenosis (r = 0.69, P < 0.001), and a good and negative correlation to target lesion lumen area (r = −0.70, P < 0.001). Postprocedural improvement in CTFC showed a modest correlation to acute lumen gain (r = 0.5, P < 0.05). With respect to culprit arteries, pre and postintervention IVUS parameters and CTFC, and net CTFC change after stenting were not different (P > 0.05). However, uncorrected TFC of LAD was significantly higher than both the CTFC of LAD and TFC of the other two coronary arteries (P < 0.05). We conclude that CTFC is closely correlated to target lesion luminal area and luminal % area stenosis whereas a modest correlation is present between improvement in CTFC and acute luminal gain due to stenting. Results from different coronary arteries with comparable IVUS parameters seem to support the validity of a correction in TFC.
- International Heart Journal刊行会の論文
著者
-
Yuce Murat
Department Of Cardiology Gaziantep University School Of Medicine
-
Kirma Cevat
Department Of Cardiology Kartal Kosuyolu Yuksek Ihtisas Education And Research Hospital
-
Ozdemir Nihal
Department Of Cardiology Kartal Kosuyolu Yiiksek Ihtisas Education And Research Hospital
-
Kaymaz Cihangir
Department Of Cardiology Kartal Kosuyolu Yiiksek Ihtisas Education And Research Hospital
-
Turan Fikret
Department Of Cardiology Kosuyolu Heart And Research Hospital
-
Ozkan Mehmet
Department Of Cardiology Kartal Kosuyolu Heart Training And Research Hospital
-
Kaymaz Cihangir
Department of Cardiology, Kosuyolu Heart & Research Hospital
-
Akçay Murat
Department of Cardiology, Kosuyolu Heart & Research Hospital
-
Akçay Murat
Department of Cardiology, Kosuyolu Heart & Research Hospital
関連論文
- Chronic Carbon Monoxide Exposure Is Associated with the Increases in Carotid Intima-Media Thickness and C-Reactive Protein Level
- Relationship Between Endothelial Function and Coronary Risk Factors in Patients With Stable Coronary Artery Disease
- Early Effects of Percutaneous Mitral Valvuloplasty on Left Atrial Mechanical Functions
- Contribution of Plasma Matrix Metalloproteinases to Development of Left Ventricular Hypertrophy and Diastolic Dysfunction in Hypertensive Subjects
- Fragmented QRS Is Predictive of Myocardial Dysfunction, Pulmonary Hypertension and Severity in Mitral Stenosis
- Acute Cigarette Smoking-Induced Hemodynamic Alterations in the Common Carotid Artery : A Transcranial Doppler Study
- Effect of Smoking on Endothelial Function and Wall Thickness of Brachial Artery
- Aortic Elastic Properties in Patients With Hypertensive Response to Exercise
- Clinical and Procedural Predictors of No-Reflow Phenomenon After Primary Percutaneous Coronary Interventions : Experience at a Single Center
- Long-Term (3-5 Years) Clinical and Angiographic Follow-up Results of Coronary Stenting in Elderly Patients
- Parachute-like mass at the superior vena cava occurring after diagnostic right heart catheterization evaluated with real-time three-dimensional transesophageal echocardiography
- Intravascular Ultrasound Correlates of Corrected TIMI Frame Count.