Human cts18.1 gene : chromosomal localization and PH-domain analysis

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概要

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• The human cts18.1 gene has high homology with the cytohesin gene family. By PCR analysis of a human monochromosomal somatic cell hybrid DNA panel, the cts18.1 gene was localized to chromosome 19. Diversity values of synonymous and nonsynonymous substitutions indicate that negative selection has occurred in the pleckstrin-homology (PH) domain of the cytohesin gene family. The phylogenetic tree calculated by the neighbor-joining method suggests that cts18.1 and cytohesin-2 genes are more closely related to each other than either of them is to the CLM-2 gene in the analysis of cDNA of the PH domain.

• 日本遺伝学会の論文

著者

• Kim Heui-soo

  Department Of Psychiatry Warneford Hospital University Of Oxford

• Kim Heui-soo

  Department Of Cellular And Molecular Biology Primate Research Institute Kyoto University

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• Human cts18.1 gene : chromosomal localization and PH-domain analysis
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