Micrococcus pyogenes var. aureus(209P)におけるカナマイシン抵抗の遺伝学的研究〔英文〕
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Mutations to kanamycin resistance in Micrococcus pyogenes var. aureus. strain 209P, occur by way of an obligatory multi-step pattern, unlike the patterns of kanamycin resistance in mycobacteria, which are facultative single-step (facultative multi-step) patterns.Kanamycin resistance is closely related with slow growth.Mutations to kanamycin resistance were accompanied with simultaneous mutations to slow growth, and mutations to fast growth in slow-growing kanamycin-resistant mutants were accompanied with simultaneous mutations to kanamycin sensitiveness. It was suggested thus that both slow growth and kanamycin resistance belong to the same locus.
- 日本遺伝学会の論文
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