チャイニ-ズハムスタ-培養細胞におけるロテノン誘発核内倍加の有糸分裂〔英文〕

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概要

• 論文の詳細を見る

• Endoreduplication was induced by rotenone with an extremely high frequency (approximately 90% of all the metaphases) in cultured Chinese hamster cells. Endoreduplicated cells were fixed without colchicine or hypotonic treatment, and chromosomal configurations were examined in various mitotic stages. The two sister chromosomes of each diplochromosome at late prophase were widely separated except the centromeric region, but they became gradually paired along the total length as the cell cycle progressed to metaphase. The anaphase cells underwent multipolar division, resulting in three or four aneuploid daughter cells. Indirect immunofluorescence staining using anti-β tubulin antibody revealed tripolar or tetrapolar spindles and unusual equatorial plates.

• 日本遺伝学会の論文
• 1993-06-25

著者

• Matsumoto K

  Laboratory Of Genetic Toxicology Institute Of Environmental Toxicology

• Matsumoto Kyomu

  Laboratory Of Genetic Toxicology The Institute Of Environmental Toxicology

• OHTA Toshihiro

  Laboratory of Genetic Toxicology, Institute of Environmental Toxicology

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• チャイニ-ズハムスタ-培養細胞におけるロテノン誘発核内倍加の有糸分裂〔英文〕

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