分娩後子宮内膜炎発症牛の分娩前後における免疫反応

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概要

• 論文の詳細を見る

• Determining the immune responses to the development of endometritis during the peripartum period may assist in the development of more efficient reproductive management regimens for dairy herds. In this study, we compared the peripartum immune responses of dairy cows that develop endometritis by 4 weeks postpartum (n=11) to cows that did not develop this disease (n=19). Blood samples were collected 1 week before calving, just after or during calving, and then at weeks 1, 2, 3, and 4 postpartum. Cows that developed endometriris had significantly higher total leukocyte, neutrophil, lymphocyte, and monocyte counts than the control cows (P<0.05) at all time points. The leukocytes from cows that developed endometritis were significantly less phagocytic than those from control cows at all sampling time points (P<0.01). The serum TNFα concentrations of the control cows decreased linearly from the prepartum time point (P=0.0029), but the endometritis cows showed a different profile (P>0.05). As a result, the serum TNFα concentrations were greater in the endometritis group (P<0.01) than in the control group during the third and fourth weeks postpartum. The greater total leukocyte numbers and neutrophil, lymphocyte and monocyte counts, and the maintenance of elevated serum TNFα levels in the cows with endometritis may be due to infection in the postpartum period. Furthermore, the decreased phagocytic capacity of leukocytes during the peripartum period, including at the prepartum time point, makes cows more susceptible to postpartum endometritis.

• 日本繁殖生物学会の論文

著者

• Na Ki-jeong

  College Of Veterinary Medicine Chungbuk National University

• Kim Ill-hwa

  韓国

• Kim Ill-Hwa

  College of Veterinary Medicine, Chungbuk National University

• Yang Nhan-Pyo

  College of Veterinary Medicine, Chungbuk National University

• Kim Ill-hwa

  Laboratory Of Theriogenology College Of Veterinary Medicine Chungbuk National University

• YANG Mhan-Pyo

  College of Veterinary Medicine, Chungbuk National University

• Kim Ill-hwa

  College Of Veterinary Medicine Chungbuk National University

• Yang Mhan-pyo

  College Of Veterinary Medicine Chungbuk National University

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