Induction of Apoptosis in DLD-1 Human Colon Cancer Cells by Peridinin Isolated from the Dinoflagellate, Heterocapsa triquetra
スポンサーリンク
概要
- 論文の詳細を見る
Peridinin, which is uniquely present in dinoflagellates, is one of the most abundant carotenoids found in nature. We evaluated the apoptotic effect of peridinin on DLD-1 human colorectal cancer cells. Peridinin significantly reduced the cell viability in a dose-dependent manner (0–20 μM) and induced apoptosis by activating both caspase-8 and caspase-9. Our findings could be important for the high-performance utilization of marine bioproducts.
- 社団法人 日本農芸化学会の論文
著者
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IMAI Ichiro
Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University
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NAGAO Akihiko
National Food Research Institute
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HIRATA Takashi
Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University
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SUGAWARA Tatsuya
Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University
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SAKAI Shota
Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University
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YAMASHITA Kyoko
Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University
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ASAI Akira
National Food Research Institute
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SHIRAISHI Tomotaka
Division of Applied Biosciences, Graduate School of Agriculture, Kyoto University
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