Bovine immune colostral antibody against verotoxin 2 derived from Escherichia coli O157:H7-resistance to proteases and effects on verotoxin 2 in small intestine of beagle dogs
スポンサーリンク
概要
- 論文の詳細を見る
Resistance to intestinal proteases and efficacy against verotoxin (VT) 2 of a colostral antibody administered orally via catheter were investigated in beagle dogs. Bovine colostral antibody remained in the small intestine for 2 hours, whereas little serum antibody remained at 1.5 hours after administration. The bovine colostral antibody was not inactivated by proteases in the small intestine. Furthermore, the antibody activity of S-IgA did not change until 2 hours after administration; however, the activity of IgG and IgM antibodies decreased by two-thirds and two-fifths at 2 hours after administration, respectively. Seven beagle dogs inoculated with Escherichia coli (E. coli) O157:H7 producing VT2 were administered bovine colostral antibody or bovine colostral whey without antibody. With administration of bovine colostral whey without antibody, the amount of VT2 in feces decreased gradually after administration and increased again at 5 days after inoculation, while bovine colostral antibody significantly reduced the amount of VT2 in feces the day after administration. In addition, 9 beagle dogs were administered bovine colostral antibody, bovine plasma antibody or saline. The amount of VT2 in feces also significantly reduced rapidly after administration of bovine colostral antibody than administration of bovine plasma antibody or saline.
- 麻布大学の論文
- 2009-03-31
麻布大学 | 論文
- 研究科分 鶏の福祉ケージにおける設備配置と空間利用--砂浴び場および巣箱の配置が行動,健康状態および生産反応に及ぼす影響 (平成19年度麻布大学公的研究助成金事業研究成果報告)
- イノシシの行動制御技術開発のための嗅覚・聴覚刺激を用いた研究(I.大学院重点特別・研究科特別経費,平成18年度麻布大学公的研究助成金事業研究成果報告)
- 広域輸送される肥育素牛のストレスおよび動物福祉レベルの評価(I.大学院重点特別・研究科特別経費,平成18年度麻布大学公的研究助成金事業研究成果報告)
- 産卵鶏におけるバタリーケージの再評価 : 福祉ケージとの比較による多面的検討(I.大学院重点特別・研究科特別経費,平成18年度麻布大学公的研究助成金事業研究成果報告)
- 産卵鶏におけるケージ飼育の再評価 : 代替飼育法との比較による多面的検討