The molecular basis of induction and formation of tunneling nanotubes
スポンサーリンク
概要
- 論文の詳細を見る
Tunneling nanotubes (TNTs) and associated structures are recently recognized structures for intercellular communication. They are F-actin containing thin protrusions of the plasma membrane of a cell and allow a direct physical connection to the plasma membranes of remote cells. TNTs and associated structures serve as mediators for intercellular transfer of organelles as well as membrane components and cytoplasmic molecules. Moreover, several pathogens were shown to exploit these structures to spread among cells. Because of their contribution to normal cellular functions and importance in pathological conditions, studies on TNTs and related structures have accelerated over the past few years. These studies have revealed key molecules for their induction and/or formation; HIV Nef and M-Sec can induce the formation of TNTs in coordination with the remodeling of the actin cytoskeleton and vesicle trafficking.
- Springer-Verlagの論文
- 2014-04-01
Springer-Verlag | 論文
- Augmenting a (k-1)-vertex-connected multigraph to an l-edge-connected and k-vertex-connected multigraph
- Development of Taenia saginata asiatica metacestodes in SCID mice and its infectivity in human and alternative definitive hosts
- Effects of fire-derived charcoal on soil properties and seedling regeneration in a recently burned Larix gmelinii/Pinus sylvestris forest
- Carbon dioxide insufflation during endoscopic retrograde cholangiopancreatography reduces bowel gas volume but does not affect visual analogue scale scores of suffering: a prospective, double-blind, randomized, controlled trial
- Diversity of Freshwater Thioploca Species and Their Specific Association with Filamentous Bacteria of the Phylum Chloroflexi