<原著論文>秋田県における劇症肝炎の臨床的検討

概要

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A multi-institutional survey of fulminant hepatitis (FH) was conducted in Akita Prefecture between 1992 and 1994. From questionaires sent to 33 hospitals, a total of 12 patients were collected from four individual core hospitals. The twelve patients consisted of 5 patients with acute form (FHA) and 7 with subacute form (FHS) of the disease, with survival rates of 40% and 29%, respectively. Etiologically, the incidence of type B was 3 out of 5 patients with FHA, while 3 out of 7 with FHB. From the Laboratory findings, GOT, GPT, and WBC appeared to be high in FHA, while total bilirubin was high in FHB. With respect to major complications, infections (64%) and DIC (50%) were the most common. Of specific therapies to prevent liver necrosis and/ or to promote liver regeneration, G-I therapy (75%) BCAA rich amino acids (100%), and hemofiltration (42%) were the most frequently applied. No positive correlations between these specific therapies and survival rates were observed, although 2 of the 5 patients treated with a combination of plasma exchange and hemodiafiltration regained consciousness.
秋田医学会の論文
1996-03-31