痴呆画像定量的診断法の基礎研究

概要

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Dementia has been diagnosed by means of subjective method (MMS, HDS-R etc.), which are not objective and demand clinical staffs trainings. Several physiological methods are under, developing, using eye dilatation by medicine (Scinto 1994) or eye constriction by light reflex (Shi 1998). As physicians are accustomed to diagnose many diseases by medical images, some visual method is also needed to diagnose dementia. In this study a new method is proposed, which measures the area of hippocampus in the dementeds' MRI coronal brain images. The result shows a good relationship between the hippocampus area % to the whole brain and the severity of the dementia. A mathematical model of brain atrophy in the demented is proposed and computer simulations are executed with good coincidence to the measured data of subjective as well as objective dementia diagnosing methods.
長岡技術科学大学の論文
2000-03-29