Chemical synthesis of novel taurine-containing uridine derivatives
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概要
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Recently, novel taurine-containing uridine derivatives were discovered in mammalian mitochondrial tRNAs, and these modified ribonucleosides existed at the first position of the anti-codon. This paper describes the chemical synthesis of these novel uridine derivatives, 5-taurinomethyluridine (τm5U) and 5-taurinomethyl-2-thiouridine (τm5s2U). These taurine-containing uridine derivatives were synthesized in the good yields by the reaction of the corresponding S-hydroxymethyluridine derivatives with taurine under basic conditions.
- Oxford University Pressの論文
- 1905-06-24
Oxford University Press | 論文
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