第12回徳島医学会賞受賞論文バイアグラ(一般名:クエン酸シルデナフィル)の使用経験と前後研究による効果評価(1)来院者の特徴

概要

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Since Sildenafil became available in Japan five years ago, 208 outpatients with ErectileDysfunction（ED）have consulted the Ogura Shinryosho Clinic in Tokushima City, Japan.On August 31st 1999, an article in the Tokushima Newspaper warned readers of the possibleside effects of Sildenafil including heart attacks. After the publication of this article, thenumber of patients in this clinic dropped by 80%. The mean age of the patients in thisstudy was 57.2 with a distribution between 29 and 84. The morbidity period of ED is 35months, and it is described as decreasing logarithmically ; only 22 outpatients in this studyexperienced symptoms occurring over six years. Several patients in this study experiencedpast medical problems including Diabetes Mellitus（18.3%）, heart disease（14.5%）, andbenign prostatic hyperplasia（12.4%）. Pigmentary retinal degeneration（PRD）is classifiedas one of Sildenafil’s contraindications. Although no patients experienced PRD in thisstudy, over 50 male patients in the prefecture of Tokushima have been diagnosed with PRD.It should be noted that there are possible complications associated with taking Sildenafilbefore the onset of PRD and Usher Syndrome.
2004-08-25