Atypical Clinical Presentation of Thrombotic Thrombocytopenic Purpura Just after Percutaneous Coronary Intervention

概要

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Thrombotic thrombocytopenic purpura （TTP） is a life-threatening illness associated with cardiovascularsurgery, infection and medications. We report a case of a 77-year-old female patient with acute myocardial infarction（AMI） treated with percutaneous coronary intervention and suffered TTP immediately afterwards. This wassuccessfully treated with plasma exchanges. Differential diagnosis of the thrombocytopenia was important and assaysfor the activities of von Willebrand Factor-cleaving protease, its inhibitor and heparin-induced thrombocytopenia（ HIT）antibody were helpful to differentiate TTP from other conditions, including HIT and disseminated intravascularcoagulation. Intensivists should be aware of an atypical presentation of TTP associated with AMI.
2011-12-26