Cardiac Event Risk in Japanese Subjects Estimated Using Gated Myocardial Perfusion Imaging, in Conjunction With Diabetes Mellitus and Chronic Kidney Disease
スポンサーリンク
概要
- 論文の詳細を見る
Background: Cardiac event risk is estimated using quantitative gated myocardial perfusion imaging (MPI) and clinical background in patients with ischemic heart disease. The aim of the present study was to calculate major cardiac event risk and tabulate it in the Heart Risk Table for clinical use of risk stratification. Methods and Results: Multivariate logistic regression was performed based on a multicenter prognostic database (Japanese Assessment of Cardiac Events and Survival Study by Quantitative Gated Single-photon emission computed tomography [J-ACCESS investigation]) using MPI (n=2,395). The risk of major cardiac events (cardiac death, non-fatal myocardial infarction and heart failure requiring hospitalization) was estimated using age, ejection fraction (EF), estimated glomerular filtration rate (eGFR) and presence of diabetes mellitus (DM). Age-matched standard eGFR was determined in 77 subjects. Major cardiac event risk was calculated using the equation: risk (%/3 years)=1/(1+Exp(-(-4.699-0.0151×eGFR+0.7998×DM+0.0582×age+0.697×SSS-0.0359×EF))×100, where SSS refers to summed stress scores. Risk was determined without eGFR (the initial version) and using the present formula with eGFR (revised version), with consistent results. DM and chronic kidney disease were major determinants of cardiac events. Conclusions: Cardiac event risk was estimated using MPI defect score and left ventricular EF in conjunction with eGFR and the presence of DM. The risk table might be used for risk evaluation in Japanese patients undergoing MPI. (Circ J 2012; 76: 168-175)
- 2011-11-19
論文 | ランダム
- 樹脂成形工程におけるロット編成融合型スケジューリング手法
- 21653 衝撃力を受ける鋼構造筋かいの耐震安全性評価に関する研究 : その1 二丁掛け山形鋼筋かいの実大実験
- 地震力を受ける鋼構造筋かいの耐震安全性評価に関する実験的研究(その3) : 保有耐力接合設計条件式の提示(構造系)(北陸支部)(1990年度支部研究発表梗概)
- 地震力を受ける鋼構造筋かいの耐震安全性評価に関する実験的研究(その2) : みぞ形鋼筋かい・2丁掛け山形鋼筋かいの耐震安全性評価(構造系)(北陸支部)(1990年度支部研究発表梗概)
- 地震力を受ける鋼構造筋かいの耐震安全性評価に関する実験的研究(その1) : 単一山形鋼筋かいの耐震安全性評価(構造系)(北陸支部)(1990年度支部研究発表梗概)