Transfer profile of intramuscularly administered tetrodotoxin to artificial hybrid specimens of pufferfish, Takifugu rubripes and Takifugu niphobles.
スポンサーリンク
概要
- 論文の詳細を見る
Tetrodotoxin (TTX) was intramuscularly administered to artificially hybridized specimens of the pufferfish Takifugu rubripes and Takifugu niphobles to investigate toxin accumulation in hybrids, and TTX transfer/accumulation profiles in the pufferfish body. In the test fish administered 146 MU TTX in physiologic saline, TTX rapidly transferred from the muscle via the blood to other organs. Toxin transfer to the ovary rapidly increased to 53.5 MU/g tissue at the end of the 72-h test period. The TTX content in the liver and skin was, at most, around 4-6 MU/g tissue, and in the testis it was less than 0.01 MU/g tissue. On the other hand, based on the total amount of toxin per individual (% of the administered toxin), the skin and the liver contained higher amounts (20-54% and 2-24%, respectively), but the amount in the liver rapidly decreased after 8-12 h, and fell below the level in the ovary after 48 h. These findings suggest that part of the TTX is first taken up in the liver and then transferred/accumulated in the skin in male specimens and in the ovary in female specimens.
論文 | ランダム
- The Use of Fibrous Polymer Materials in Capillary Electrochromatography (Review)
- 分離精製および分析法 (炭素第三の同素体フラーレンの化学) -- (基礎)
- フラーレンの有機合成化学的展開-C_のシリルメチル誘導体の合成と有機,無機フラーレン誘導体合成への応用-
- 分析の研究室における情報環境
- A-4-33 適応形IIRフィルタの収束性(A-4.信号処理,一般講演)