高分解能ガスクロマトグラフ質量分析計を用いた異径キャピラリーカラムによる血液中ポリ塩化クアテルフェニルの迅速測定
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概要
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The polychlorinated quaterphenyl (PCQ) concentrations in blood are important discriminative parameters in yusho patient. In this study, a rapid analytical method for PCQ using different diameter capillary column (rapid-Rtx65TG) with high-resolution gas chromatograph high-resolution mass spectrometer (HRGC/HRMS) instead of the gas chromatograph electron capture detector (ECD/GC) was developed. Using different diameter capillary columns, the analysis time of the HRGC/HRMS was drasticallyshortened, and the detection sensitivity was improved. In the rapid-Rtx65TG column, a small-bore capillary column (length 1m, I.D. 0.1mm) was connected with the inlet side of the GC, and behind that column, a large-bore capillary column (length 15mm, I.D. 0. 53mm) for octadecachloroquaterphenyl (ODCQ) analysis was connected. In the HRGC/HRMS measurement of ODCQ by the rapid-Rtx65TG column, the minimum limit of detection for the apparatus was 0.4 pg, and the minimum limit of etermination for the blood was 0.008 ppb. On ECD/GC in the conventional method and HRGC/HRMS in this study, the PCQ concentration in blood including yusho patients and yusho suspected persons was almost equivalent.
- 2011-04-25
論文 | ランダム
- ハルダー, 「芸術と祭祀」, Halder, Alois, Kunst und Kult. Zur Asthetik und Philosophie der Kunst in der Wende vom 19. zum 20. Jahrhundert. Verlag Karl Alber Freiburg, Munchen, 1964. 95S.
- AMPA/KAINATE RECEPTOR-MEDIATED PRESYNAPTIC MODULATION AT CEREBELLAR GABAERGIC SYNAPSES(Physiology)(Proceedings of the Seventieth Annual Meeting of the Zoological Society of Japan)
- PRECISE DETERMINATION OF HEMOLYMPH ECDYSTEROID TITER IN THE LAST LARVAL INSTAR OF THE SILKWORM, BOMBYX MORI(Endocrinology)Proceedings of the Sixty-Third Annual Meeting of the Zoologiacal Socistry of Japan
- IN VITRO RECONSTRUCTION OF MOUSE HAIR GERMS FROM DISSOCIATED SKIN CELLS(Developmental Biology)(Proceeding of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
- パヴロフ, 「美学史寄与」, Todor Pawlow, Beitrage zur Geschichte der Asthetik, Aufbau-Verlag Berlin, 1963, 190S.