海産動植物特殊成分の化学的性質並びに其の薬理作用に関する研究-要約-
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In the previous paper, the author reported about the pancreas of marine mammala as the resources of insulin in Hokkaido. After that, an improved method for its extraction has been devised, and a pure white powder which was used intact as medicine was obtained. By the studies on the medicinalfunction of marine animal-insulin, it was ascertained that the insulin, alikethe one obtained froln oxen, had much favorable effect for the tratment ofdiabetic symptoms of rabbits, which were induced by the administration ofglucose (peros), adrenalin or alloxan (injection). Sargalin, a basic compound newly isolated from Sdrgassum confusumAg., has its molecular formula C20H24O8N4K. As a rnedicinal function, the sargalin exhibits the blood-sllgar lowering property and when injected tegether with insulin to the animals, intensified its effectiveness increasingly. Another new bromic phenol compound was also isolated from Symphocladiagracilis Falk., molecular formula of which was C6H5O4Br. By the studies on the medicinal function, this bromic phenol was shown to be distinctively effective to the round worm (Ascaris lumbricoides) as a vermifuge; its effective concentraticn lies 0.03-0.05% in Bunge's solution. Theauthor guessed that the phenol was one of the vermifugal components of sea weeds. It was also proved that bromic-phenol shows nearly as much inhibiting action as N.D.G. A. against the oxidation of vitamin A.
- 鹿児島大学,カゴシマ ダイガク,Kagoshima Universityの論文
鹿児島大学,カゴシマ ダイガク,Kagoshima University | 論文
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