[Case Reports] Successful pregnancy foilowing gamete intrafallopian transfer in a patient with a transverse vaginal septum: case report

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publisherWatanabe, Yoh[Abstract] Transverse vaginal septa (TVSs) are rare congenital, obstructive vaginal anomalies resulting from a defect of vertical fusion during embryogenesis of the vagina and are generally diagnosed at the time of pregnancy in association with obstetric complications. TVSs also contribute to infertility. Surgical treatment, such as resection or fenestration of the TVS, is generally indicated. However, the optimal treatment of infertile patients with TVS has not been established, and few cases of conception following clinical management have been reported. We report the first case of a successful pregnancy in a patient with a perforate TVS in the lower one-third of the vagina following gamete intrafallopian transfer (GIFT). She presented at 30 years of age for the evaluation of primary infertility. The TVS was located in the vaginal canal ending at a depth of approximately 3 cm, with a single opening, 1-2 mm in diameter, observed at the end of the vaginal cavity. The TVS was considered to be an etiologic factor for infertility. Our patient achieved a pregnancy via GIFT and gave birth to healthy twins by cesarean section. Laparoscopic GIFT is a useful procedure for infertile women with TVS.