Induction of pluripotency by defined factors.
スポンサーリンク
概要
- 論文の詳細を見る
Somatic cells can be reprogrammed into pluripotent stem cells by introducing a combination of several transcription factors. The induced pluripotent stem (iPS) cells from a patient's somatic cells could be useful source of cells for drug discovery and cell transplantation therapies. However, most human iPS cells are made by viral vectors, such as retrovirus and lentivirus, which integrate the reprogramming factors into host genomes and may increase the risk of tumor formation. Studies of the mechanisms underlying the reprogramming and establishment of non-integration methods contribute evidence to resolve the safety concerns associated with iPS cells. On the other hand, patient-specific iPS cells have already been established and used for recapitulating disease pathology.
- 2010-10-01
論文 | ランダム
- ワークショップ企画や災害調査に役立つ地域調査演習(9)現地での調査
- ワークショップ企画や災害調査に役立つ地域調査演習(8)対象地域の自然災害に関する調査(その2)
- ワークショップ企画や災害調査に役立つ地域調査演習(7)対象地域の自然災害に関する調査(その1)
- ワークショップ企画や災害調査に役立つ地域調査演習(6)地域の自然条件を調べる(その2)気象/河川
- ワークショップ企画や災害調査に役立つ地域調査演習(5)地域の自然条件を調べる(その1)地形