In vitro regeneration of kidney from pluripotent stem cells.
スポンサーリンク
概要
- 論文の詳細を見る
Although renal transplantation has proved a successful treatment for the patients with end-stage renal failure, the therapy is hampered by the problem of serious shortage of donor organs. Regenerative medicine using stem cells, including cell transplantation therapy, needs to be developed to solve the problem. We previously identified the multipotent progenitor cells in the embryonic mouse kidney that can give rise to several kinds of epithelial cells found in adult kidney, such as glomerular podocytes and renal tubular epithelia. Establishing the method to generate the progenitors from human pluripotent stem cells that have the capacity to indefinitely proliferate in vitro is required for the development of kidney regeneration strategy. We review the current status of the research on the differentiation of pluripotent stem cells into renal lineages and describe cues to promote this research field.
- 2010-10-01
論文 | ランダム
- 諸磯・浮島式土器の変遷と型式間の影響関係--折衷土器成立の意味について考える
- 縄文時代前期の東京湾における漁撈の様相
- 縄文時代後期前葉の東京湾における漁労活動の様相--魚類獲得活動を中心として
- 東北地方北部における縄文時代前期から中期への移行期の様相--円筒下層c・d式土器の変遷と大木式土器との関係
- 大木6式土器の変遷とその地域性--縄文時代前期末葉の東北地方中・南部の土器編年