[原著］内胆汁瘻症例 : 胆嚢病変の組織学的検討

概要

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A case of a 75 year - old female with mucosal carcinoma of the gallbladder in cholecystoduodenal fistula was described, and then the resected gallbladders in twenty one cases of biliary enteric fistula were histologically studied to investigate their morphological features, and discuss relation between fistula and genesis of gallbladder cancer. The gallbladders were small in size and contracted. The walls of the gllabladders were thickened. Histologically, they showed inflammatory changes ( fibrous thickening of the wall, inflammatory infiltrates and intimal thickening of the artery ) that were characteristic in this disease. On the other hand, the mucosa was relatively well preserved. It revealed mucous gland metaplasia in 95.2 per cent and goblet cell metaplasia in 52.4 per cent. The incidence of metaplasia was similar to that in patients with cholelithiasis, and lower than that in gallbladder cancer patients. Based on these results, reflux of enteric contents into the gallbladder may cause persistent inflammation of the gallbladder, but may not correlate to the genesis of the gallbladder cancer.
琉球大学医学部の論文
1982-00-00