Studies on the ocular hypotensive effect of Diamox
スポンサーリンク
概要
- 論文の詳細を見る
<p>In our studies on the hypotensive effect of Diamox by intravenous injection, we have arrived at the following conclusions. 1. Ocular tension falls and the flow of aqueous humor becomes sluggish. 2. Diamox inhibits the activity of carbonic anhydrase, and the concentrationsof HCO3-, K+, Cl- and glucose are markedly altered.3. Protein increases both in blood and aqueous humor, but no change in protein fraction can be observed in blood.4. Diamox in no way affects the metabolism. 5. It seems that Diamox brings about the change in the specific gravityof blood, making the latter either more diluted or more concentrated. From these, we conclude that the mechanism of the loweing of ocular tension by Diamox seems to lie in the fact that it inhibits the activity of carbonic anhydrase, and that consequent alteration in the concentrations of HCO3- and other ions accompanied by the change in osmotic pressure as well as a slight decrease of water in tissue all bring about the fall in the ocular tension. However, Diamox seems to have nothing to do withaqueous humor in so far as active transport or permeability are concerned.</p>
- Okayama University Medical Schoolの論文
Okayama University Medical School | 論文
- Influencing Factors for Dietary Behaviors of Patientswith Diabetic Nephropathy
- Mechanistic Analysis of Resistance to REIC/Dkk-3-induced Apoptosis in Human Bladder Cancer Cells
- Relationship of psychological factors with physical activity stage of change in prime-and middle-aged Japanese
- The Half-life of Ascaris lumbricoides Prevalence in Japanese School Children
- Effects of mask fitness and worker education on the prevention of occupational dust exposure