Nephrin is an important component of the barrier system in the testis.
スポンサーリンク
概要
- 論文の詳細を見る
<p>Nephrin, a gene product of the congenital nephrotic syndrome of the Finnish type (NPHS1), is a 1242-residue putative transmembrane protein of the immunoglobulin family of cell adhesion molecules. The expression of this gene is localized in rat and human glomerular epithelial cells. Here we report the expression of nephrin in various tissues other than the kidneys in mice. The expression of nephrin mRNA in various tissues of mice, including the kidneys, testes, spleen, thymus and brain, were first investigated by the RT-PCR method, and it was shown that a high level of nephrin mRNA could be detected in the testes of mice 1-6 weeks old. In situ hybridization revealed the expression of the nephrin gene in the Sertoli cells. Additionally, immunofluorescent staining studies indicated that nephrin was colocalized with anchoring protein ZO-1 in the mouse testis. From these results, it is inferred that nephrin is an important component of the barrier system in testes.</p>
論文 | ランダム
- Propranolol使用における心筋代謝ならびに血行動態について : 第24回日本循環器学会九州地方会
- マウスNa+H+逆輸送担体cDNAクローニングとその組織発現の検討 : 口述発表 : 第57回日本循環器学会学術集会
- β-Adrenergic blockadeの血行動態及び心筋代謝に及ぼす影響
- 蛋白代謝に関する研究 (第5報) : 大動脈弁障害犬における体蛋白系代謝の動態について : 第23回日本循環器学会九州地方会
- 心筋代謝に関する研究 : ヒトうっ血性心不全における心筋遊離脂肪酸代謝に関する研究 : 第23回日本循環器学会九州地方会