肺小細胞癌化学療法実施例における重複癌の発生に関する研究
スポンサーリンク
概要
- 論文の詳細を見る
Development of double cancer was evaluated in 337 small cell lung cancer patients who had received intensive chemotherapy with or without radiotherapy. Of them, 14 patients (4.2%) developed a second malignancy: non-small cell lung cancer in six, stomach cancer in four, acute myelogenous leukemia in two, liver cancer in one, and esophagus cancer in one. The relative risk for the development of double cancer calculated by person-year method utilizing age and sex adjusted cancer incidence in Japan was 2.75-fold (P<0.01). The risk of non-small cell lung cancer (8.75-fold) and acute myelogenous leukemia (37.82-fold) was particularly high. The cumulative risk for the development of double cancer was 2.0% at 1 year, 4.1% at 2 years, 14.3% at 3 years, and 100% at 8.1 years. Of 27 patients who survived disease-free for more than 2 years, 10 patients died; five patients (50%) died of double cancer, two died of infectious disease, and only three patients died from recurrent small cell lung cancer. These findings indicate that a cautious follow-up program for the detection of double cancer is indicated in patients with small cell lung cancer.
論文 | ランダム
- 1-H-6 非線形競争モデルにおける動的挙動の解析(シミュレーション(1))
- 1-H-4 口蹄疫を例にした感染モデルの提案(シミュレーション(1))
- 1-H-3 多クラス単一サーバ待ち行列の定常分布の重負荷近似 : 基礎変数の二次モーメント条件の仮定のもとで(確率統計)
- 1-H-2 「スポーツ振興投票の実施等に関する法律施行規則」における指定試合無開催時の期待値(確率統計)
- 1-H-1 Multi-data filtering method in keystroke dynamics-based user authentication